Medical Research Studies
Long-term effects of percutaneous estrogens and oral progesterone on serum lipoproteins in postmenopausal women
January, 1987 - Conclusion: This study looked at 847 women 45-64 yrs old and put them in groups receiving either Premarin (horse urine estrogen), Prempro (horse urine estrogen plus artificial form of progesterone), Premarin plus natural progesterone or placebo. The women who received the estrogen combined with natural progesterone had better HDL (good cholesterol) levels than those who received estrogen combined with progestin (artificial progesterone). Also blood sugar was shown to be increased in the group having estrogen with progestin but not in the group that used estrogen plus natural progesterone. Finally, the study showed that the natural progesterone protected the uterine lining from the cancer promoting effects of estrogen alone as well as progestin. So the authors concluded that estrogen combined with natural progesterone is a better choice than estrogen combined with progestin.
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